The University of Kansas (KU), BEREXO Inc., Bittersweet Energy Inc., Kansas Geological Survey, and the Kansas State University evaluated potential CO2 storage sites, including saline aquifers and depleted oil reservoirs, within the Ozark Plateau Aquifer System (OPAS) in south-central Kansas. The study focused on the Wellington Field, with an evaluation of the CO2-enhanced oil recovery (EOR) potential of its Mississippian chert reservoir and the storage potential in the underlying Cambro-Ordovician Arbuckle Group saline reservoir. A larger study of the saline reservoir was undertaken over a 33 county area in south-central Kansas to evaluate regional CO2 storage potential. Additionally, the EOR potential of the Chester and Marrow Sandstone reservoirs is being evaluated. This study integrated well data, seismic, geologic, and engineering approaches to evaluate CO2 storage potential. The project estimated the CO2 storage potential of multiple formations by constructing integrated geological models followed by reservoir simulation studies. The effort collected available data, drilled and logged three new wells through the Arbuckle Group, cored a portion of the injection and confining zones, and performed chemical and physical analyses on the samples. Analysis of the geochemistry of formation fluids was conducted, and a simulation of fluid flow and geochemical interactions was performed.