Montana State University is developing new mineralization precipitation technologies capable of sealing near-wellbore leakage pathways under a variety of pressure and temperature conditions in the presence of CO₂ and brine to help ensure CO₂ permanence within the storage formation. The minerals are promoted by enzymatic and thermal degradation of urea which results in mineral precipitation. The minerals can withstand significantly greater temperature than certain microbe precipitation techniques explored during previous development efforts. The project is combining the use of laboratory testing at elevated temperatures and simulation modeling to determine the most applicable mineral sealing strategy. The selected strategy will be deployed in a field experiment in the Montana State University’s Danielson Test Well which contains multiple fluids including brine and CO₂ (Figure 1). The longevity of the mineral seal is being assessed with laboratory, modeling, and well logging and characterization techniques. The project team is building on its previous successes with biomineralization technology development by targeting the use of the identified active catalyst enzyme (instead of the entire cell) and direct thermal hydrolysis of urea to drive mineral precipitation. This will facilitate engineered mineralization sealing at greater depths and higher temperatures than is currently possible with biomineralization technology.