DOE's National Energy Technology Laboratory (NETL) has developed a comprehensive, full-market assessment tool to assist in research and development (R&D) and policy planning. The Gas Systems Analysis Model (GSAM) evaluates and quantifies the direct impacts of potential technology improvements due to R&D, including unique combinations of enhanced reservoir performance (for specific reservoir conditions), decreased investments or operating costs (for specific site or operator characteristics), and reduced exploration and development risk (in defined basins, regions, or resource types) for individual reservoirs nationwide. In addition, GSAM can simulate a variety of diverse policy alternatives, including specific tax, environmental, and regulatory structures, directly estimating their economic implications for future domestic gas exploration and production (E&P) operations. The detailed, quantitative assessments of technology impacts produced by GSAM are based on full market impacts, reservoir to burnertip. Key technology improvements and public policy initiatives can be evaluated to determine regional and national impacts on gas production, end-use demand, various industry investment activities, and jobs, as well as the resulting natural gas prices, at the wellhead, at various city-gates, and by region and end-use sector. As currently structured, GSAM provides technology, policy, and environmental impact assessments needed to focus and coordinate public and private R&D activities. GSAM provides DOE decision-makers and the natural gas industry with key details on the market impacts of alternative technologies and policies. A better understanding of the direct implications of policy and programmatic alternatives will help DOE to significantly and directly increase the effectiveness and value of its Natural Gas Program.