The Transformative Power Generation Program aims to advance science, engineering, and technology by inventing, integrating, maturing, and commercializing coal combustion power technologies and systems to enhance the nation’s energy production and protect the environment for future generations. The program develops technologies to improve performance and extend the life of existing power plants. Research also focuses on next generation modular coal-fired power plants providing stable power generation with operational flexibility and high efficiency, as well as advanced combustion technologies such as oxy-combustion and chemical looping combustion—technologies that provide options for coal-fired power generation in a carbon-constrained future. The program uses a multi-pronged and coordinated approach to identify and perform research through in-house research and development (R&D), as well as cost-shared R&D with external partners in academia, industry, and other national laboratories. Transformative Power Generation technologies will be market-driven with the best technologies, growing deployment opportunities in an increasingly challenging power generation market.